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Efficacy and safety of a new dentifrice containing Chinese herb extracts for gingivitis: a double-blind randomized placebo parallel controlled trial

Efficacy and safety of a new dentifrice containing Chinese herb extracts for gingivitis: a double-blind randomized placebo parallel controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015742
Enrollment
Unknown
Registered
2018-04-18
Start date
2017-11-01
Completion date
Unknown
Last updated
2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingivitis

Interventions

The experimental group:Use the experimental toothpaste
The control group:Use the blank-control toothpaste

Sponsors

West China Hospital of Stomatology Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Ranging in age from 18 to 70 years old, gender not limited; 2. The body in good health, have a daily habit of brushing your teeth, teeth can be detected more than 20; 3. The subjects have gingivitis; more than 60% of check points GI=1, improved Quigley - Hein plaque index PI >=1.0; 4. No recent experimental study at the same time to participate in other similar study; 5. Sign the informed consent, can complete the clinical trial as required.

Exclusion criteria

Exclusion criteria: 1. Patients with severe periodontitis, pulpitis or mouth is open cavities, the mucosa lesion; 2. The test of toothpaste ingredients allergies or other oral hygiene products; 3. For nearly one month oral treatment or the use of antibiotics; 4. Have a bad prosthesis, or undergoing Orthodontic treatment; 5. Pregnancy or lactation subjects.

Design outcomes

Primary

MeasureTime frame
Plaque index;Gingival index;Bleeding index;Bleeding on probing proportion;

Countries

China

Contacts

Public ContactLi Cheng

West China Hospital of Stomatology Sichuan University

dentistcl@foxmail.com+86 15882453615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026