Gastroesophageal Reflux Disease, Vocal Cord Polyps
Conditions
Interventions
vocal polyp group:Nil
none vocal polyp group:Nil
Sponsors
the Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Vocal polyp group: Patients diagnosed as vocal polyp by laryngoscopy,have a vocal cord polyp resection.Patients volunteered for this study and signed informed consent. None vocal polyp group: Patients have the laryngoscopy examination shows no vocal polyp.Patients volunteered for this study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) have a history of chronic disease,such as asthma or neurological disease; 2) have a history of malignancy; 3) can not complete the study for any reason, such as language comprehension disorders, mental illness or can not tolerate the test; 4) have a history of taking antiacid drugs or prokinetic agent a week before the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h PH-impedance monitoring;saliva pepsin concentration;immunohistochemical stain of vocal polyp;immunofluorescence of vocal polyp; | — |
Secondary
| Measure | Time frame |
|---|---|
| GerdQ scores; | — |
Countries
China
Contacts
Public ContactYazhu Zou
Chongqing Medical University
Outcome results
None listed