Clinical study of traditional Chinese medicine Yushen reciption in the intervention of early chronic allograft nephropathy

Clinical study of traditional Chinese medicine Yushen reciption in the intervention of early chronic allograft nephropathy.

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800015689

Enrollment

Unknown

Registered

2018-04-15

Start date

2018-05-01

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic allograft nephropathy

Interventions

Treatment group:CNI (CsA/FK506 + MMF + Pred) plus Yushen Recipe

Control:CNI (CsA/FK506 + MMF + Pred)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) conform to the diagnostic criteria of chronic allograft nephropathy and the dialectical standard of traditional Chinese medicine; 2) aged 18~70 years; 3) after 12 months of transplantation; 4) serum creatinine (Scr) < 250 mol/L; 5) no hemodialysis or peritoneal dialysis treatment; 6) no severe acute and chronic digestive tract disease; 7) willing to participate in the trial and sign informed consent.

Exclusion criteria

Exclusion criteria: 1) renal function damage caused by acute rejection, virus infection, acute CsA/FK506 renal toxicity, obstruction / reflux, renal vascular stenosis and other pathological changes in clinical and / or renal allograft pathology; 2) combined with serious diseases such as heart, liver and blood system; 3) women in pregnancy or lactation; 4) people who were allergic to this medicine; 5) psychosis.

Design outcomes

Primary

Measure	Time frame
creatinine;Cystatin;eGFR;CD4 T;CD8 T;Urinary albumin / creatinine ratio;Interleaf arterial resistance index;Arcuate artery resistance index;Resistance index of segmental artery;	—

Countries

China

Contacts

Public ContactQin Yan

Shanghai General Hospital

yanqin12@hotmail.com+86 18602194937

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026