Obesity Hypoventilation Syndrome
Conditions
Interventions
A:Traditional BPV, AVAPS-BPV
B:AVAPS-BPV, Traditional BPV
Sponsors
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants with a primary diagnosis of stable OHS visiting our sleep respiratory laboratory during January 2016 to June 2017, aged 20-70 years, were consecutively recruited.
Exclusion criteria
Exclusion criteria: 1) other causes of chronic respiratory failure such as COPD hypothyroidism, chest wall abnormalities and neuromuscular diseases; 2) acute respiratory acidosis (aggravated in past two weeks RR>30 times a minute PH<7.35) 3) tracheal intubation during the last three months; 4) any other form of ventilatory support had been received before; 5) other organ dysfunction or failure, such as severe infection, hemodynamics, uncontrolled cardiac failure, severe arrhythmia, unstable angina pectoris, gastrointestinal perforation or bleeding; 6) disorders of dysphoria, delirium or unconsciousness, or psychophysical inability to coordinate or protect airway or provide written informed consent; 7) too much or viscous airway secretion; 8) had received surgery or suffered in face, neck, esophagus and stomach recently; 9) pneumothorax without drainage; 10)upper airway obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| arterial blood gases; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep stage;norcturnal oxygen saturation;tidal volume;minute volume;titration pressure; | — |
Countries
China
Contacts
Public ContactXiao Yi
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital
Outcome results
None listed