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Clinical study for the effect of salvianolic acid on plaque stability and angiogenesis

Clinical study for the effect of salvianolic acid on plaque stability and angiogenesis

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015677
Enrollment
Unknown
Registered
2018-04-14
Start date
2018-04-15
Completion date
Unknown
Last updated
2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

massive cerebral infarction

Interventions

salvianolic acids:application of injection salvianolic acids
Routine treatment control group:General routine treatment after cerebral infarction

Sponsors

Shanxi People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. aged 40-75 years old; 2. patients with large area cerebral infarction within 72 hours of onset; For the first time in 3. cerebral vascular disease, or had a history of cerebrovascular disease, but did not have limb paralysis sequelae, and does not affect the NIHSS score, mRS score before the onset of stroke is less than or equal to 2 points; 4. large area cerebral infarction of internal carotid artery system by cranial nuclear magnetic DWI examination; 5. in the case of informed consent, we can accept and cooperate with blood test, NMR and TCD examination. The sample content was 40 cases.

Exclusion criteria

Exclusion criteria: 1. History of neurologic disease; 2. There was a history of severe hypertension, diabetes and connective tissue disease. Vascular examination showed obvious atherosclerosis, especially in severe arterial stenosis; 3. Complication of severe liver and kidney function; 4. Recent history of surgery; 5. Contraindication with magnetic resonance imaging; 6. Anaphylaxis to Salvia miltiorrhiza.

Design outcomes

Primary

MeasureTime frame
MRI-ASL;MRI-DWI;VEGF;bFGF;

Countries

China

Contacts

Public ContactHu Fengyun

Shanxi People's Hospital

fengyun71@163.com+86 13834233638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026