Efficacy and safety of balanced hydroxyethyl starch infusion using a goal-directed fluid therapy algorithm in elderly orthopedics patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800015653

Enrollment

Unknown

Registered

2018-04-12

Start date

2018-04-16

Completion date

Unknown

Last updated

2018-04-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedic diseases

Interventions

Ringer's lactate solution:Ringer's lactate solution infusion

HES Saline group:Hydroxyethyl starch 130/0.4 in a saline solution infusion

HES Balanced:Hydroxyethyl starch 130/0.4 in a balanced electrolyte solution

Eligibility

Sex/Gender

All

Age

65 Years to 90 Years

Inclusion criteria

Inclusion criteria: Male or female patients; 65~90 years old; Elective major orthopedics surgery; General anesthesia.

Exclusion criteria

Exclusion criteria: Patients of ASA-class III or IV; body weight 29; Abnormal liver or renal function; Abnormal coagulation function; Hg < 10g/dl or HCT < 30%; Potassium, sodium or chloride above the upper limit of normal of the laboratory; Known history of a mental or neurological disorder; known hypersensitivity and with contraindications to HES or any of the excipients; Severe cardiac arrhythmias; Other contraindications to anesthesia or surgery.

Design outcomes

Primary

Measure	Time frame
Efficacy;Safety;	—

Countries

China

Contacts

Public ContactFuhai Ji

The First Affiliated Hospital of Soochow University

jifuhai@hotmail.com+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026