myelodysplastic syndromes
Conditions
Interventions
Case series:traditional chinese formula containing arsenic
Sponsors
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients must be diagnosed as myelodysplastic syndromes according to WHO classification system ; 2. Patients must be more than 18 years old and less than 75 years old; 3. Bone marrow blast cell count of patients must be less than 5%, and peripheral blood neutrophils of patients must be more than 0.5 × 10^9/L, and peripheral blood platelets of patients must be more than 20 × 10^9/L, and without severe bleeding and fever; 4. Patients must be without serious complication of heart and liver kidney; 5. Patients must have no other clinical studies participating.
Exclusion criteria
Exclusion criteria: Patients have one of the following conditions: allergic to indigo or realgar; pregnant or breast-feeding women; strong demand for fertility; mental disorders.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Karyotype analysis;Morphological examination of bone marrow cells; | — |
Primary
| Measure | Time frame |
|---|---|
| Peripheral blood count;mRNA expression of MBD2 and TET1, TET2 and TET3;Changes of 5m C and 5hm C; | — |
Countries
China
Contacts
Public ContactXiu Yonggang
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed