Polycystic ovarian syndrome
Conditions
Interventions
Sponsors
Guangdong Women and Children Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Compatible with the diagnosis of PCOS-IR; 2. Aged from 18 years to 45 years; 3. No use drugs before recruiting; 4. Volunteered to participate in the clinical study; None of the above nonconformities is included in the study.
Exclusion criteria
Exclusion criteria: 1. pregnant or lactating women; 2. PCOS women with cardiovascular, liver or kidney disease; patients who may have tumors; 3. G6PD deficiency; 4 BMI<18kg/m2; 5. the patients take hormones or drugs which affect the secretion of insulin in nearly three months; 6. Take berberine or metformin allergy ,abuse drugs or alcohol; 7. poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose;1 hour plasma glucose;2 hour plasma glucose;3 hour plasma glucose;Fasting insulin;1 hour insulin;2 hour insulin;3 hour insulin;homeostasis model assessment;height;weight;waist circumference;hip circumference;WHR;Total cholesterol;triglycerides;Low density lipoprotein cholesterol;High density lipoprotein cholesterol;Uric acid;Follicle-stimulating hormone;Luteinizing hormone;estradiol;prolactin;Sex hormone binding protein;dehydroepiandrosterone;testosterone;Free testosterone index;F-G grades; | — |
Countries
China
Contacts
Public ContactLi Li
Guangdong Women and Children Hospital
Outcome results
None listed