none
Conditions
Interventions
Midazolam:Intranasal midazolam
Combine dexmedetomidine with midazolam:Intranasal dexmedetomidine and midazolam
Sponsors
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
1 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1) Voluntary participation in the trial and signing of the informed consent statement; 2) Aged 1 to 6 years old; 3) Elective surgery with an operating time of no more than 1 hour; 4) ASA I to II.
Exclusion criteria
Exclusion criteria: 1) BMI28; 2) there are nasal diseases; 3) There are factors that affect the communication between researchers and children; 4) There are poorly experiences about surgery and anesthesia; 5) Participants had nervous system, cardiovascular system, endocrine system and abnormal liver and kidney function; 6) There is a history of allergies to the studied drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of cooperation during anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety before induction of anesthesia;The degree of cooperation during intranasally administration;The comfort during intranasally administration;The level of sedation;Separation score;Pediatric anesthesia emergence delirium;Post hospital behavior questionaire;Heart rate;Blood pressure; | — |
Countries
China
Contacts
Public ContactHan Lin
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Outcome results
None listed