chronic heart failure
Conditions
Interventions
Control group:Placebo
Treatment group:Qiangxin Jieyu decoction granules
Sponsors
Jiangsu Province Hospital on Integration of Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. All the cases are definitely diagnosed with the diagnostic criteria of the Guidelines for the diagnosis and treatment of heart failure in China 2014, NYHA grade II-IV; 2. The depression screening scale PHQ-9> 9 points, and <20 points; 3. TCM dialectical typing Yin and Yang deficiency, harmful fluid Retention; 4. Aged greater than 18 years; 5. Have a junior high school or above, clear-headed, self-discipline and understanding, and able to accurately understand and fill in various scales; 6. Those who have signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Acute heart failure; 2) Patients with cardiogenic shock, acute coronary syndrome, and other diseases that may cause death; 3) Poor compliance and non-compliance with treatment requirements; 4) Those who cannot complete the rating scale independently; 5) Patients with severe liver and kidney dysfunction (ALT =120U/L, Cr = 3mg/dl), untreated malignant tumors or other serious diseases; 6) Those who need a recent need for surgical treatment of valvular heart disease and coronary heart disease; 7) Severely infected persons, Severely mental patients or pregnant women; 8) Simultaneous use of other Chinese medicines or participating in drug clinical researchers; 9) Those who are receiving carbamazepine, phenytoin, sodium valproate, gabapentin, pregabalin, venlafaxine, desvenlafaxine, milnacipran, duloxetine, tricyclic antidepressants and other antipsychotic drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression and quality of life self-rating scale;5-Hydroxytryptamine; | — |
Countries
China
Contacts
Public ContactMinglin GU
Jiangsu Province Hospital on Integration of Chinese and Western Medicine
Outcome results
None listed