Laparoscopic Cholecystectomy
Conditions
Interventions
DEX group:Intravenous dexamethasone+ peri-incisional and intraperitoneal ropivacaine
NS group:Intravenous normal saline + peri-incisional and intraperitoneal ropivacaine
BK group:Intravenous normal saline + peri-incisional and intraperitoneal normal saline
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients who were scheduled for elective laparoscopic cholecystectomy under general anesthesia because of gall bladder polyps, chronic cholecystitis or gallstones were enrolled in this study, aged between 18 and 75 years, with an American Society of Anesthesiologists physical status classification of I to II.
Exclusion criteria
Exclusion criteria: Patients with acute cholecystitis, chronic pain diseases except gallstone disease, renal or hepatic disease, active peptic ulcer diseaseprior medication with corticosteroids usage, a history of alcohol or drug abuse, ASA physical status III or greater, contraindications to any of the drugs used in the study, and pregnancy. Moreover, patients were excluded if the operation was converted to an open procedure, a drainage catheter was inserted or the duration of surgery 80 min.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score within 48 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| total dosage of opioids drug;side effects of nausea and vomiting; | — |
Countries
China
Contacts
Public ContactJun Ying
The Second Affiliated Hospital of Nanchang University
Outcome results
None listed