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Intervention on HMGB1 Protection against Recurrent Abortion with Unexplained Causes

Intervention on HMGB1 Protection against Recurrent Abortion with Unexplained Causes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800015403
Enrollment
Unknown
Registered
2018-03-28
Start date
2018-04-01
Completion date
Unknown
Last updated
2021-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unexplian recurrent spontaneous abortion

Interventions

A:none
B:received aspirin with one month
C: received aspirin with two month
D:none

Sponsors

The First Affiliated Hospital of Anhui Medical University Address
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Aged from 20 to 40 years old; (2) women with unexpliain recurrent spontaneous abortion.

Exclusion criteria

Exclusion criteria: 1. Chromosome abnormalities; 2. Anatomical factors; 3. Endocrine diseases; 4. Infection; 5. Autoimmune abnormalities.

Design outcomes

Primary

MeasureTime frame
expression of HMGB1 and related inflammatory factors (IL-1beta, TNF-alpha, TGF beta 1, etc.);—

Contacts

Public ContactXiaofeng Xu

The First Affiliated Hospital of Anhui Medical University

xxf0550@126.com+86 13505691991

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026