Triple Negative Breast Cancer
Conditions
Interventions
control group:placebo
Sponsors
The First Afliliated Hospital of AMU (Southwest hospital)
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old; 2. The pathological diagnosis of breast invasive ductal carcinoma; 3. Complete the modified radical mastectomy; 4. Postoperative pathology confirmed with lymph node metastasis; 5. TNM Stage II-III; 6. Molecular classification of Triple Negative Breast Cancer; 7. Within 14-28days at the end of the time of surgery and chemotherapy; 8. According to the NCCN(2017.V3)guidelines for chemotherapy; 9. If need to radiotherapy, receive radiation therapy according to the plan; 10. No local recurrence and distant metastasis; 11. Liver and kidney functionScr=1.5ULNALT(AST) =2.5ULN; 12. No other history of malignancy; 13. Eastern Cooperative Oncology Group (ECOG) =2; 14. Have the ability to compliance protocol; 15. Volunteered for the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women, or plan a pregnancy during the study period; 2. With severe heart, liver, kidney, endocrine system disease patients, and the expected lifetime < 2 years; 3. Allergic to Huaier Granule or its composition; 4. Incomplete or have residual tumor resection surgery; 5. No according to radiation scheme; 6. Not according to NCCN guidelines for chemotherapy; 7. Bilateral breast cancer patients; 8. Clinical or radiographic indicates a distant metastases; 9. Participation in any other clinical trial within three months; 10. Poor compliance or have conditions that are considered not suitable for this study investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| disease-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-year overall survivals;Karnofsky;EORTC QLQ-C30; | — |
Countries
China
Contacts
Public ContactJiang Jun
The First Afliliated Hospital of AMU (Southwest hospital)
Outcome results
None listed