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Effects of sevoflurane and propofol on intraoperative inflammation and postoperative pulmonary complications in patients undergoing head and neck surgery with free flap

Effects of sevoflurane and propofol on intraoperative inflammation and postoperative pulmonary complications in patients undergoing head and neck surgery with free flap

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015347
Enrollment
Unknown
Registered
2018-03-25
Start date
2018-04-05
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck tumor

Interventions

1:Propofol + Remifentanil
2:Sevoflurane + Remifentanil

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years old; 2. Patients with free head and neck tumors (temporal bone, forearm); 3. Operating time = 4h. 4. canet score = 26 points

Exclusion criteria

Exclusion criteria: 1. Pulmonary artery stenosis, pulmonary hypertension and congestive heart failure, complex heart deformities; 2. Severe chest wall malformation, acute obstructive pulmonary disease (AECOPD), acute bronchitis, and uncontrolled asthma; 3. History of mental illness; 4. Patients or their families refused to participate in clinical trials.

Design outcomes

Primary

MeasureTime frame
Postoperative pulmonary complications;—

Countries

China

Contacts

Public ContactZhou Dan

Peking University Third Hospital

zhoudan2011@163.com+86 18613839301

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026