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Effects of probiotics on inflammation and intestinal microflora in patients with atopic dermatitis

Study on the effect and mechanism of probiotics on patients with atopic dermatitis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015330
Enrollment
Unknown
Registered
2018-03-23
Start date
2018-03-26
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis

Interventions

Placebo group:Placebo
Oligosaccharide group:Oligosaccharide
Bifidobacterium F35 group:1 billion Bifidobacterium F35 strains
Lactobacillus plantarum CCFM8610 group:1 billion Lactobacillus plantarum CCFM8610

Sponsors

The Peoples' hospital of Tinghu district of Yancheng city
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of Hanfin and Rajka; 2. Aged 7 to 60 years old; 3. Have not taken with probiotics (such as lactic acid bacteria, bifidobacteria, etc.) yogurt, beverages and etc. In the past two months; Adhere to the requirements of taking probiotic productions for 2 months; Cooperate with the survey And the collection of blood samples, feces and other biological samples; 4. Volunteers who sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Short-term or long-term use of antibiotics; 3. Accompanied by diabetes, cardiovascular,history of malignant disease Complications and other any interference with the test results evaluation of skin diseases; 4. Enteritis, etc.; 5. Accompanied by mental illness.

Design outcomes

Primary

MeasureTime frame
Fecal flora;Fecal flora genomics;Blood routine;Urine routine;Fecal routine;All Blood Cells Analysis;Serum IgE;

Secondary

MeasureTime frame
Height;Weight;Waist circumference;liver function;Blood lipid level;

Countries

China

Contacts

Public ContactWenwei Lu

Jiangnan University

luwenwei@jiangnan.edu.cn+86 18762691080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 2, 2026