Ischemic cerebrovascular diseases
Conditions
Interventions
rapid-metabolism group:antiplatelet agent
mediate-poor-metabolism group:antiplatelet agent
Sponsors
Department of Neurology, Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. men or women aged 18-80 years old; 2. diagnosed with TIA or Ischemic Stroke; 3. for patients without symptoms;1)carotid atherosclerosis plaque( intima-media thickness>=1.5mm) detected by carotid artery ultrasound;2)Ischemic lesions or cerebral arteriosclerosis comfirmed by CT or MRI; 4. patients or their legal representative who have signed informed consent.
Exclusion criteria
Exclusion criteria: 1. patients with cerebral hemorrhage or hemorrhagic cerebral infarction comfirmed by CT or MRI; 2. coma patients; 3. patients with a platelets count <80×10^9/L, or bleeding tendency disease such as blood disease, peptic ulcer; 4. patients with malignant tumor, severe infection, impaired liver function or renal dysfunction; 5. pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADP and AA-induced platelet inhibition rates; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of ischemic events at 30 days; | — |
Countries
China
Contacts
Public ContactSheng Tan
Department of Neurology, Zhujiang Hospital of Southern Medical University
Outcome results
None listed