Efficacy of Premedication with N-acetylcysteine during Upper Gastrointestinal Endoscopy Examation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800015281

Enrollment

Unknown

Registered

2018-03-20

Start date

2018-04-10

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early cancer of upper digestive tract

Interventions

Group A:Lidocaine gel

Group B:pronase+simethicone

Group C:600mg N-acetylcysteine

Group D:1200mg N-acetylcysteine

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Aged between 18 and 70 years (include 18 and 70 years old); (2) Need to take upper gastrointestinal endoscopy; (3) Inform consent has been obtained.

Exclusion criteria

Exclusion criteria: (1) Have contraindication of gastroscopy; (2) digestive ulcer or tumor which have been diagnosed; (3) bronchial asthma which have been diagnosed; (4) Digestive diseases which threat to life; (5) Undergo surgery of upper digestive tract; (6) serious insufficiency of heart, liver or kidney; poor vital signs (SBP>150mmHg, DBP>90mmHg, HR>100, SpO2<90%); (7) mental sickness or neurosis; (8) Pregnancy or nursing mothers; (9) Do not want to participant in this trail; (10) Allergic to the medicine of the trail.

Design outcomes

Primary

Measure	Time frame
score of gastric body;score of fundus;score of antrum;	—

Secondary

Measure	Time frame
pathological results;Small lesions;number of flushing;quantity of water;time of upper gastrointestinal endoscopy;adverse event;	—

Countries

China

Contacts

Public ContactZHai Huihong

Beijing Friendship Hospital, Capital Medical University

zhaihuihong@263.net+86 15710076855

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026