liver injury
Conditions
Interventions
Gold Standard:Routine MRI qualitative diagnosis and blood biochemical indexes.
IDEALIQ 
FF 
value 
and 
sequences 
diffusion 
coefficient 
filling 
f 
Sponsors
Cancer Hospital of Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patient inclusion criteria: 1) advanced colorectal cancer patients with advanced colorectal cancer and untreated patients were highly suspected by cytology, histopathological confirmation or imaging joint examination; 2) the imaging evaluation of nuclear magnetic function and the examination of laboratory related indicators and the basic normal function of the heart, liver, kidney and bone marrow of all patients were basically normal; 3) willing to join the project research, agreed to take at least four to six cycles of chemotherapy (5 fluorouracil, and oxaliplatin into Iraq for kang based on effective) for preoperative neoadjuvant chemotherapy drugs, and can fit on a regular basis in our blood biochemical examination and imaging follow-up review, and sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1) a history of drug-induced liver injury (traditional Chinese medicine (TCM), anti-tuberculosis drug, antipyretic analgesic), liver, kidney function was abnormal before chemotherapy, metabolic and endocrine disease (lipid metabolic disorders, type 2 diabetes), blood disease, repeated a large number of patients with history of blood transfusion; General nuclear magnetic examination contraindication (in the body of metal implants, metal stent implantation, cardiac pacemaker, claustrophobic); Unable to withstand nuclear magnetic breath or free breathing trigger scanner; The image artifact of the patient was obvious and affected the image analyzer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fat fraction; | — |
Countries
China
Contacts
Public ContactQian Wang
Cancer Hospital of Chinese Academy of Medical Sciences
Outcome results
None listed