Acute and chronic pain after Radical mastectomy
Conditions
Interventions
Ultrasound guided thoracic paravertebral nerve block group(T):Before the induction of anesthesia, 20ml of 0.375% ropivacaine was injected into the thoracic paravertebral space between T4 and T5 on t
ultrasound guided erector spinae plane block group (E):Before the induction of anesthesia, 20ml of 0.375% ropivacaine was injected into the erector spinae plane at T4 level on the surgical side under
Control group (C):Before the induction of anesthesia 20ml of saline was injected into the Subcutaneous tissue at T4 level on the surgical side under ultrasound guidance
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: A total of 90 patients undergoing Radical mastectomy under general anesthesia were selected; ASA I-II; aged 20-80 years; ethical, voluntary and signed informed consent.
Exclusion criteria
Exclusion criteria: Severe spine deformity; puncture site infection; anticoagulant therapy; morbid obesity (BMI> 40kg/m2); local anesthetic drug allergy; severe heart and lung disease; liver and kidney dysfunction; patients with mental illness, speech and communication disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative dose of opioids in 24h?48h after surgery;2h, 4h, 8h, 24h, 48h after operation, VAS scores for rest and exercise, and rest and exercise VAS scores for 3 months after operation;Postoperative nausea and vomiting, dizziness, respiratory depression, adverse reactions to urinary retention; | — |
Secondary
| Measure | Time frame |
|---|---|
| The first time and the number of compressions of analgesic pump within 48 hours;postoperative analgesia satisfaction score;Changes in blood pressure and heart rate before and after skin incision;Wake-up time and extubation tim;Days of Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactZhenzhong Luo
The Second Affiliated Hospital of Nanchang University
Outcome results
None listed