Chronic atrophic gastritis
Conditions
Interventions
Experimental group:treat with proton pump inhibitor for 1 month,meanwhile folic acid tablets and weifuchun tablets for 6 months
Control group:treat with proton pump inhibitor for 1 month,meanwhile folic acid tablets for 6 months
Sponsors
Wuhan Union Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years old, can tolerate digestive endoscopy; 2. Pathological biopsy confirmed as chronic atrophic gastritis; 3. Suitable for medical treatment; 4. Voluntarily join the experiment and sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients have history of gastric resection,acute gastrointestinal hemorrhage, advanced gastric cancer, and other gastrointestinal malignant tumors; 2. Suffer from diseases that cannot tolerate gastroscopy, including coagulopathy, renal insufficiency, severe cardiopulmonary disease, and fluorescein sodium hypersensitivity; 3. Pregnancy and lactation women; 4. Patients without legal capacity, or have medical and ethical reasons that influence the conduct of the study; 5. Due to the use of certain banned drugs, it is impossible to evaluate the efficacy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biopsy pathology results;symptom;Endoscopic diagnosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pepsinogen and Gastrin;HP detection; | — |
Countries
China
Contacts
Public ContactLin Rong
Wuhan Union Hospital
Outcome results
None listed