nonalcoholic steatohepatitis
Conditions
Interventions
Two groups:diet and exercise
Sponsors
Affiliated Hospital of Hangzhou Normal University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years old male and female; 2. bmi<35kg/m2, in line with the 2010 Chinese Medical Association of Liver disease, fatty liver and alcoholic liver disease group developed the "nonalcoholic fatty liver disease guidelines for diagnosis and treatment" diagnostic criteria; 3. liver histology confirmed as NAFLD patients; 4. The patient understands and is willing to sign an informed consent letter.
Exclusion criteria
Exclusion criteria: 1. in the past 5 years, alcohol and/or drug abuse and dependence; 2. female average daily alcohol intake >10g/days, male average daily alcohol intake >20g/days; 3. combined with other acute and chronic active liver disease (viral hepatitis, hereditary scarlet disease, hepatolenticular degeneration, ?-resistance to trypsin deficiency, alcoholic liver disease, drug-related liver disease); 4. cirrhosis patients; 5. The Heart function is not complete, the heart function grade is 2, 3 or 4; 6. with heart pacemaker patients; 7. uncontrolled hypertension; 8. renal insufficiency, blood creatinine > normal upper limit; 9. pregnant or lactating women; 10. female early Pregnancy screening test positive, or the observation period does not want to contraceptive person; 11. The combination of HIV infection; 12. cannot accept MRI examination; 13. Long-term use of antibiotics (> 1 weeks); 14. uncontrolled hypothyroidism (upper limit of normal tsh>2 times); 15. Other researchers do not think that the completion of clinical trials; 16) can not sign the informed consent of the person.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glutamic-pyruvic transaminase;glutamic oxalacetic transaminase;Controlled attenuation index;gamma-glutamyltransferase;alkaline phosphatase; | — |
Countries
China
Contacts
Public ContactShi Junping
Affiliated Hospital of Hangzhou Normal University
Outcome results
None listed