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Measurement of the Rates of Retinal Nerve Fiber Layer Thinning to Guide Management of Myopic Glaucoma Patients

Measurement of the Rates of Retinal Nerve Fiber Layer Thinning to Guide Management of Myopic Glaucoma Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015147
Enrollment
Unknown
Registered
2018-03-09
Start date
2018-04-02
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopic Glaucoma

Interventions

Two groups:Prostaglandin Analogs (PGA) and/or Carbonic anhydrase inhibitors (CAI) and/or Bromide and/or Selective Laser Trabeculoplasty (SLT) versus Travian (0.002%) once daily
Xalatan once daily
Azopt three times daily
Trusopt three times daily, 24 months

Sponsors

The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Primary open angle glaucoma patients (POAG) who are: age =18 years; best corrected VA =20/40; POAG diagnosed within 12 months at the time of recruitment and receiving not more than one IOP-lowering medication.

Exclusion criteria

Exclusion criteria: POAG with IOP>30mmHg; advanced VF loss (VF MD <-18dB in the worse eye) or defects close to fixation (any one of the paracentral points with sensitivity <10dB); pathological myopia (eyes with axial length=26mm with lacquer cracks and chorioretinal atrophy); ocular or systemic diseases that may cause VF loss or optic disc abnormalities; inability to perform reliable VF; suboptimal quality of SDOCT images; previous intraocular surgery other than uncomplicated cataract extraction; and diabetic retinopathy/maculopathy.

Design outcomes

Primary

MeasureTime frame
The proportion of eyes with VF progression;

Secondary

MeasureTime frame
The rate of change of VF mean deviation (MD);

Countries

China

Contacts

Public ContactDr. Leung Kai Shun Christopher

The Chinese University of Hong Kong

cleung21@hku.hk+852 25181430

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026