left atrial appendage occlusion (LAAO)
Conditions
Interventions
Two groups:high flow nasal cannula (HFNC) Optiflow THRIVE Inhalation 50 litres min-1, 30 minutes versus standard low flow nasal cannula Inhalation 4 litres min-1, 30 minutes
Sponsors
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Subjects undergoing left atrial appendage occlusion with deep sedation in the cardiac intervention laboratory
Exclusion criteria
Exclusion criteria: 1. Subjects who are unable to tolerate the high flow nasal cannula secondary to discomfort; 2. Subjects who are with aspiration risks and will require endotracheal intubation; 3. Severe obstructive sleep apnoea; 4. Subjects with anticipated difficult airway; 5. Subjects with chronic carbon dioxide retention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of desaturation episodes;Rate of change of arterial blood gases, including partial pressure of oxygen (PaO2), partial pressure of carbon dioxide and pH over time;Need for airway manipulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory rate;Tolerability;Postoperative outcome in the recovery unit; | — |
Countries
China
Contacts
Public ContactTeresa Hing Yan Tsang
Department of Anaesthesia and Intensive Care, Prince of Wales Hospital
Outcome results
None listed