Irritable Bowel Syndrome with small intestinal bacterial overgrowth
Conditions
Interventions
Control group:placebo
Sponsors
Third Affiliated Hospital of Army Medical University (Field Surgery Institute)
Eligibility
Sex/Gender
All
Age
16 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Male or female, aged 16 to 75 years; 2) In accordance with irritable bowel syndrome diagnostic criteria of the Roman ?, patients are diagnosised Irritable Bowel Syndrome; 3) The patients were diagnosed small intestinal bacterial overgrowth; 4) No other serious disease, mental disorders, and have ability of normal communication; 5) Signed informed consent, agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1) complicated with other serious heart, liver, kidney, respiratory, digestive, blood, endocrine system disease; 2) abnormal liver meritorious service is significant or any of the following history of liver disease: 2 times higher than normal amount of AST and ALT limit, liver cirrhosis, hepatic encephalopathy history, history of history of esophageal varices or portal vein shunt; 3) a history of renal damage evidence or the following kidney disease: serum creatinine 1.5 times higher than normal limit; The history of dialysis; History or nephrotic syndrome; 4) the combination of various acute infection, tumor and severe arrhythmia, mental system disorders, drug or alcohol addiction; 5) pregnancy or lactation; 6) nearly four weeks with application of antibiotics, acid suppression, lactulose, probiotics, or other drugs affect gastrointestinal dynamic history; 7) it is difficult to finish with the visitor, or the various factors influencing the compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SIBO eradication rate;IBS-SSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| IBS-QOL;GSRS;16S rDNA; | — |
Countries
China
Contacts
Public ContactChen Dongfeng
Third Affiliated Hospital of Army Medical University (Field Surgery Institute)
Outcome results
None listed