Gastrointestinal Tumo
Conditions
Interventions
E:use of a single dose of Etomidate in anesthesia induction
P:use of a single dose of Propfol in anesthesia induction
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients equal to or older than 65 years old(gender is not limited); 2. Hospitalized patients proposed to receive selective gastrointestinal tumor surgery in Huashan Hospital; 3. Patients of ASA grade I-II level; 4. Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1. HPA\HPT\HPG axis related diseases; 2. hepatic diseases; 3. infectious diseases; 4. use of hormone or drugs affect the secretion of the hormone(e.g. ketoconazole,Dexmedetomidine ); 5. obesity(BMI >30); 6. chronic hypoxia (COPD,OSAS); 7. oral diseases; 8. mental diseases; 9. predicted to be difficult airway; 10. known to allegic to any drugs in the protocol; 11. participate in other clinical trials in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary cortisol concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of the prophylactic use of antibiotics;The incidence of wound infection;Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactZHAO ZHANG
Huashan Hospital, Fudan University
Outcome results
None listed