hepatitis B virus–related hepatocellular carcinoma
Conditions
Interventions
1:exairesis
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. older than 18 years and less than 69 years old; 2. the first operation was in accordance with the Milan standard, the treatment was excised, and pathological biopsy is proved to be HCC; 3. at least 2 imaging examinations supported the typical imaging findings of hepatocellular carcinoma, or 1 imaging examinations with AFP > 400 g/L, or cytological and histological evidences prove to be HCC when recurrence; 4. for single tumor recurrence, tumor maximum diameter is less than 3cm; and the resection and radiofrequency ablation both can be implemented; 5. the residual liver volume was still sufficient after resection; 6. ICG-R15<20%; 7. the liver function is Chid-Pugh A, or Child-Pugh B which can return to Class A after treatment; 8. no other major organ dysfunction; 9. patients agreed to participate in the clinical trial.
Exclusion criteria
Exclusion criteria: 1. The image found extrahepatic lymph nodes or visceral metastasis, the existence of large vascular invasion, the existence of bile duct embolus in the first operation; 2. The patient combined with a malignant tumor of other organs or had a history of other malignant tumors in other organs; 3. Liver function decompensation, such as: upper gastrointestinal bleeding, refractory ascites, coagulation dysfunction and so on; 4. contraindications to surgery; 5. Patients with poor compliance and not adhered to the follow-ups; 6. Patients refused to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Routine blood test;Biochemical routine;AFP;PIVKA-II;CEA;Abdominal ultrasound; | — |
Countries
China
Contacts
Public ContactWen Tianfu
West China Hospital, Sichuan University
Outcome results
None listed