erectile dysfunction after laparoscopic total mesorectal excision of rectal cancer
Conditions
Interventions
Experience group:oral sildenafil afer operation
control group:oral placebo after operation
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Tumor has invaded surrounded organs and tissues, which could not be resected, or has distant metastasis; 2. Patients with severe respiratory insufficiency, circulatory disease or malfunction of liver and kidney; 3. Patients with Heart disease (Coronary heart disease, myocardial infarction, arrhythmia, etc); 4. patients with taking nitrates; 5. patients with a history of spontaneous erectile erection; 6. patients with visual interference; 7. patients with drepanocytosis or coagulation diaorders.
Exclusion criteria
Exclusion criteria: 1. patients who not meet the criteria of inclusion; 2. patients with severe pelvic autonomic nerves damage during operation; 3. subjects take other interventions which will influence the outcome of the test; 4. Researchers think that subjects should terminate the test from a medical point of view; 5. patients require to terminate and withdraw from the test.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| The changes of pre- and postoperative erectile function, ESV and PSV.;The intraoperative and postoperative complication.;The side effects of sildenafil tablet.; | — |
Primary
| Measure | Time frame |
|---|---|
| The incidence of erectile dysfunction at 12 months after laparoscopic total mesorectal excision of rectal cancer.; | — |
Countries
China
Contacts
Public ContactZhenhong Zou
The Second Affiliated Hospital, Nanchang University
Outcome results
None listed