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PBMS-IMRT reduces the incidence of the hematologic toxicity of patients with cervical cancer receiving concurrent chemoradiotherapy: A prospective study

PBMS-IMRT reduces the incidence of the hematologic toxicity of patients with cervical cancer receiving concurrent chemoradiotherapy: A prospective study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015069
Enrollment
Unknown
Registered
2018-03-06
Start date
2018-04-10
Completion date
Unknown
Last updated
2018-05-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical cancer

Interventions

PBMS Group:Pelvic Bone Marrow Sparing Intensity Modulated Radiotherapy
Control group:No

Sponsors

The first hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Eligible patients comprised clinical Stage Ib2 - IIIb cervical carcinoma and no previous history of chemotherapy or pelvic irradiation (according to the FIGO clinical stage of 2015 NCCN guidelines); (2) Aged between 20 and 70 years with ECOG score < 3 (as defined by Zubrod-ECOG-WHO); (3) All the patients will be treated with concurrent Cisplatin chemotherapy and IMRT.

Exclusion criteria

Exclusion criteria: (1) Patients or their families refused to participate in this study; (2) Patients treated with extended-field radiation therapy were excluded; (3) Patients who interruped treatment were excluded; (4) Patients who with blood related diseases or occupational exposures such as paint, decoration, nail industry, etc.

Design outcomes

Primary

MeasureTime frame
white blood cell count (WBC);Hemoglobin;Absolute neutrophil count;Platelet count;

Countries

China

Contacts

Public ContactLi Guang

The first hospital of China Medical University

13804058616@163.com+86 13804058616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 26, 2026