Mild Cognitive Impairment
Conditions
Interventions
Dual-task Group:Aerobic dance
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) The patients aged 55 to 85 years men or women; 2) Stable clinical state with diagnosis of mild cognitive impairment according to the diagnostic criteria in 2013; 3) The patients and caregiver voluntarily participated in the trial and signed the informed consent; 4) With memory impairment for more than 3 months, but have normal activities of daily living; 5) Score in MMSE was >24; 6) Score in MOCA =26; 7) Score in clinical dementia rating (CDR) was 0.5.
Exclusion criteria
Exclusion criteria: 1) Diagnosed as Vascular Dementia according to NINDS-AIREN standards; 2) Hachinskilnchemic score (HIS) scale score >4; 3) Patients cannot cooperated with cognitive assessment(including sight loss and hearing loss, severe dysphonia); 4) The patients had alcohol or drug dependency in the past six months; 5) The patients were participating in other clinical trials; 6) The patients were illiterate; 7) The patients had brain structure lesions which may cause cognitive impairment, such as traumatic brain injury and intracranial space-occupying lesions, or had congenital mental retardation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting state fMRI;Gait speed;Cognitive assessments;plasma amyloid ß; | — |
Countries
China
Contacts
Public ContactZhu Yi
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed