Valvular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age between 40 years old and 60 years old; 2. Scheduled to undergo cardiopulmonary bypass and general anesthesia in this hospital; 3. The patient's cognitive state is mormal; 4. Classification of cardiac function to class II - III (using the classification of cardiac function by the New York Heart Association).
Exclusion criteria
Exclusion criteria: 1) Refuse to participate; 2) Emergent surgery or trauma patients; 3) Preoperative cognitive impairment characterized by Mini-Mental State Examination (MMSE) of 23 or less; 4) Preoperative history of stroke, schizophrenia, major depression, Parkinson's disease, epilepsy, or dementia; 5) Inability to communicate in the preoperative period due to illiteracy, language difficulties, or significant hearing or visual impairment; 6) Those with preoperative ASA classification of 4 or who are unlikely to survive for more than 24 hours after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| hospital stay;ICU stay;medical cost;the duration of intubation;adverse event; | — |
Countries
China
Contacts
Xiangya Hospital of Central South University