pain after total knee arthroplasty
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) undergone unilateral total knee arthroplasty; (2) aged 25-80 years old; (3) BMI 18-25 kg/m2; (4) ASA I-II.
Exclusion criteria
Exclusion criteria: (1) regional anesthesia contraindications (e.g. local infection); (2) having psychological problems or history of mental illness; (3) having serious cardiovascular disease, liver and kidney dysfunction or stroke; (4) allergy to local anesthetic or opioid drug; (5) having history of use of alcohol, drug abuse, opioids or town static drugs before operation; (6) having language difficulties or can not correctly understand the visual analog pain score; (7) having long-term use of opioids (3 months or daily use of opioids, almost every day); (8) having a limb neuropathology or history of lower extremity surgery or trauma and preoperative diabetes; (9) having peripheral neuropathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| muscle strength of four biceps femoris at 8 h, 12 h, 24h, 72 h, 96 h, 120 h after surgery;Timed up and go test (TUG test) at 48h, 72 h, 96 h, 120 h after surgery;visual analogue scale (VAS) at 4 h, 6 h, 12 h, 24h, 72 h, 96 h, 120 h after surgery;The sensory block level of 4h, 6h, 8h, 12h, 24h, 48 h after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative satisfaction at 4h, 6h, 8h, 12h, 24h, 48 h after operation;the rate of nausea and vomiting at 4h, 6h, 8h, 12h, 24h, 48 h after operation;the rate of retention of urine at 4h, 6h, 8h, 12h, 24h, 48 h after operation;the rate of tumble after operation;neural complications;Toxic reaction; | — |
Countries
China
Contacts
Foshan ChanCheng Center Hospital