Overweight and Obese Patients Anesthesia
Conditions
Interventions
experimental group A:rocuronium and sugamadex for the Laparoscopic anesthesia
experimental group D:rocuronium and sugamadex in the surgical anesthesia for obstructive sleep disorder syndrome
control group B:cisatracurium and neostigmine for the Laparoscopic anesthesia
control group C:rocuronium and neostigmine for the Laparoscopic anesthesia
control group E:cisatracurium and neostigmine in the surgical anesthesia for obstructive sleep disorder syndrome
control group F:rocuronium and neostigmine in the surgical anesthesia for obstructive sleep disorder syndrome
Sponsors
Department of Anesthesiology, Union hospital, Tongji medical college, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing laparoscopic surgery or surgery of obstructive sleep apnea hypopnea syndrome; 2. patients Body Mass Index=24.0kg/m2; 3. patients ASA physical status I~II.
Exclusion criteria
Exclusion criteria: 1. Drugs that have been used before surgery to influence the efficacy of muscle relaxants or neuromuscular transmission; 2. The site of muscle pine monitoring has a history of surgery or trauma in the recent month; 3. The history of hypertensive cerebral infarction, diabetes, heart disease, mental disease, and so on; 4. Anaphylaxis to non depolarizing muscle relaxants; 5. With the use of contraindications in neostigmine; 6. Suffering from a neuromuscular system or a history of small arthritis; 7. Formerly having alcoholism or drug abuse; 8. Abnormal indexes of liver and kidney function examination; 9. Preoperative examination of acid-base balance disorder; 10. Preoperative assessment of difficult airway.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative residual muscle relaxation rate;Evaluation of tracheal intubation condition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;Muscle relaxant effect;Postoperative adverse events; | — |
Countries
China
Contacts
Public ContactShanglong Yao
Tongji Medical College of Huazhong University of Science and Technology
Outcome results
None listed