Glioma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Voluntary participation and written signature of informed consent; 2. Age 18-70 years old, gender is not limited; 3. Histologically proved to be high-grade gliomas and high-risk secondary gliomas; 4. Card's score> 70; 5. Survival expected = 6 months; 6. Women of childbearing age should be guaranteed contraception during their study. 7. Hemoglobin (HGB) =100 g/L, WBC=4 × 10^9/L, Platelet (PLT) =100 × 10^9/L. Liver function: alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT) <1.5 times the upper limit of normal (ULN); total bilirubin <1.5 x ULN. (Or the relevant laboratory normal unit value) Renal Function: Serum creatinine <1.5 × ULN. 8. No serious complications, such as hypertension, diabetes, coronary heart disease and mental history; 9. No history of brain radiotherapy; no history of concurrent chemoradiotherapy; no chemotherapy within 3 months.
Exclusion criteria
Exclusion criteria: 1. The primary tumor had radiotherapy; 2. Have been targeted vascular vascular endothelial growth factor treatment; 3. The primary tumor has received chemotherapy or immunotherapy; 4. Have had other malignancies (except for cured basal cell carcinoma or cervical carcinoma in situ); 5. Subjects who have undergone other drug tests in the last month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effective rate; | — |
Countries
China
Contacts
Guizhou Cancer Hospital