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Synchrotron Radiation and Adjuvant Chemotherapy after Glioma: A Open, Multicenter Phase II Study

Synchrotron Radiation and Adjuvant Chemotherapy after Glioma: A Open, Multicenter Phase II Study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015035
Enrollment
Unknown
Registered
2018-03-02
Start date
2017-12-31
Completion date
Unknown
Last updated
2018-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioma

Interventions

1:Synchrotron Radiation
2:adjuvant chemotherapy

Sponsors

Guizhou Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Voluntary participation and written signature of informed consent; 2. Age 18-70 years old, gender is not limited; 3. Histologically proved to be high-grade gliomas and high-risk secondary gliomas; 4. Card's score> 70; 5. Survival expected = 6 months; 6. Women of childbearing age should be guaranteed contraception during their study. 7. Hemoglobin (HGB) =100 g/L, WBC=4 × 10^9/L, Platelet (PLT) =100 × 10^9/L. Liver function: alanine aminotransferase (ALAT), aspartate aminotransferase (ASAT) <1.5 times the upper limit of normal (ULN); total bilirubin <1.5 x ULN. (Or the relevant laboratory normal unit value) Renal Function: Serum creatinine <1.5 × ULN. 8. No serious complications, such as hypertension, diabetes, coronary heart disease and mental history; 9. No history of brain radiotherapy; no history of concurrent chemoradiotherapy; no chemotherapy within 3 months.

Exclusion criteria

Exclusion criteria: 1. The primary tumor had radiotherapy; 2. Have been targeted vascular vascular endothelial growth factor treatment; 3. The primary tumor has received chemotherapy or immunotherapy; 4. Have had other malignancies (except for cured basal cell carcinoma or cervical carcinoma in situ); 5. Subjects who have undergone other drug tests in the last month.

Design outcomes

Primary

MeasureTime frame
effective rate;

Countries

China

Contacts

Public ContactJin Feng

Guizhou Cancer Hospital

jinf8865@yeah.net+86 13985124806

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026