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Effects of different doses of oxycodone on median effective concentration of epidural ropivacaine in elderly patients

Effects of different doses of oxycodone on median effective concentration of epidural ropivacaine in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800015025
Enrollment
Unknown
Registered
2018-03-01
Start date
2018-05-01
Completion date
Unknown
Last updated
2018-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery for varicose veins in the lower extremity of epidural anesthesia

Interventions

Ropivacaine alone:The epidural injection of ropivacaine
Ropivacaine combined with oxycodone 5mg:Epidural injection of ropivacaine combined with 5mg oxycodone
Ropivacaine combined with oxycodone 5mg:Epidural injection of ropivacaine compound 2.5mg hydroxyketone

Sponsors

Shaoxing People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 60-85 years of age, male and female; 2. Body image index is 18-25; 3. Patients, ASA I-II; 4. Patients familiar with all the procedure and evaluation, agreed to participate in this experiment, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Exclude puncture local infection; 2. Hypersensitivity to amide local anesthetics; 3. Bleeding constitution, severe peripheral arteriosclerosis, aspirin within 1 weeks; 4. Patients with neuralgia or spinal disease.

Design outcomes

Primary

MeasureTime frame
blood pressure;heart rate;PO2;Epidural effect;The anesthesia onset time;The highest plane of the epidural;—

Countries

China

Contacts

Public ContactLi Yuhong

Shaoxing People's Hospital

yuh_li@qq.com+86 13758147990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026