Mild cognitive impairment
Conditions
Interventions
control group:milk powder
low dose group:milk powder
high dose group:milk powder
Sponsors
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) aged 45-85 years old healthy middle-aged and elderly people have the main memory of subjective memory decline; (2) memory loss course of more than 3 months, not meet the diagnostic criteria for dementia; (3) MMSE score: years of education = 6 years, then = 22 points; years of education> 6 years, = 26 points;
Exclusion criteria
Exclusion criteria: (1) taking nutritional supplements to improve cognitive function within three months prior to enrollment; (2) lactose intolerance; (3) severe liver and kidney disease, such as glomerulonephritis, nephrotic syndrome, cirrhosis, etc .; severe cardiovascular and cerebrovascular diseases; (4) Those who have a lower education level than junior middle school (5) smoking, alcoholism; (6) Those who have not signed the informed consent; (7) participated in other clinical trials within three months; (8) Persons with delirium, confusion, or other disabilities; (9) Cognitive decline caused by neurological disorders include Alzheimer's disease, Parkinson's disease, stroke, normal-pressure hydrocephalus and other brain lesions including tumors; (10) Infectious or inflammatory encephalopathy history; (11) major head injury caused by cognitive decline; (12) Beans, fish, seafood allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acetylcholinesterase;SOD;MDA; | — |
Secondary
| Measure | Time frame |
|---|---|
| FFA;blood glucose;insulin;folic acid;VB12;homocysteine;TC;TG;HDL-C;LDL-C; | — |
Countries
China
Contacts
Public ContactSheng Ge
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Outcome results
None listed