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Comparing of different blood purification modes on clearing protein-bound uremic toxins in hemodialysis patients: a prospective, single center, randomized trial

Comparing of different blood purification modes on clearing protein-bound uremic toxins in hemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014993
Enrollment
Unknown
Registered
2018-02-27
Start date
2017-07-01
Completion date
Unknown
Last updated
2018-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

uremia

Interventions

1:Low flux hemodialysis
2:High flux hemodialysis
3:High flux hemodialysis combined with hemodiafiltration
4:High flux hemodialysis ombined with hemoperfusion

Sponsors

Xinqiao Hospital, Chongqing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-70 years old male and female; (2) Confirmed uremia; (3) Patients were on a maintenance dialysis of three times per week for at least 3 months; (4) Patients with infection, tumor and other diseases during active phase were excluded; (5) Patients participate in this trial voluntarily and sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Peritoneal dialysis patients; (2) Maintenance of hemodialysis for less than three months; (3) Severe mental or neurological disorders that affect informed consent and / or adverse expression or observation; (4) Patients who were judged by the investigator as not suitable for the study.

Design outcomes

Primary

MeasureTime frame
Indoxyl sulfate;p-cresyl sulfate;—

Countries

China

Contacts

Public ContactJinghong Zhao

Department of Nephrology, Xinqiao Hospital, Chongqing

zhaojh@tmmu.edu.cn+86 13668007369

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026