Intracranial vascular occlusive diseases
Conditions
Interventions
Case series:modified indirect extra-intracranial vascular reconstruction
Sponsors
Tongji Hospital in Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: All the patients are Chinese people aged between 18 and 75 years at the time of enrollment; all the patients present with recurrent transient ischemic attack; all the patients with focal cerebral ischemia or small slice cerebral infarction are confirmed by cranial MRI; all the patients with severe stenosis or occlusion of intracranial vessels are confirmed by cranial CTA or whole brain angiography; all the patients with cerebral hypoperfusion are revealed by cranial CT perfusion imaging; all the patients recovered from stroke without physical disability (mRS=3) and mental diseases are able ti care for themselves in daily life.
Exclusion criteria
Exclusion criteria: The patients with other cerebrovascular diseases such as aneurysm or arteriovenous malformations, taking special medicines such as antiepileptic drugs or psychotropic drugs, severe chronic systemic disease (contraindication in operation) and other diseases of the central nervous system, such as craniocerebral injury, brain tumor, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| evaluation of cognitive function;cerebrovascular event;Cerebral blood flow;revascularization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuronal damage in hippocampal region; | — |
Countries
China
Contacts
Public ContactJian Hai
Tongji Hospital in Shanghai
Outcome results
None listed