achalasia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The diagnosis of achalasia patients was made on the basis of clinical symptoms, barium esophaography, esophagogastroduodenoscopy (EGD) and high resolution manometry (HRM); (2) Eckardt score >=4; (3) Aged between 18 to 70 years; (4) Without previous endoscopic or surgical treatment fro achalasia; (5) Non-sigmoid-type achalasia; (6) Patient consented to receive POEM at our hospital and signed an infromed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with severe coagulopathy (INR >2,Platelet 2 cm); (6) Other contradicitons of endoscopic examination and therapy, such as severe scoliosis, mental diseases, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eckardt Score;Esophageal high resolution manometry;complication;24 h PH testing; | — |
Secondary
| Measure | Time frame |
|---|---|
| Esophageal barium;Gastroesophageal reflux disease questionnaire scores;quality of life;Operative time; | — |
Countries
China
Contacts
the Second Xiangya Hospital of Central South University