Obstructive Sleep Apnea-hypopnea Syndrome
Conditions
Interventions
Lidocaine group:Bolus 1.0-1·5 mg/kg before induction,then 1.0-1.5 mg/kg/h until 1 h after operation
Saline control group:Control group received a normal saline bolus and an infusion to simulate the study drug
Sponsors
The Affiliated Huaian Hospital of Xuzhou Medical university/Huai 'an Second Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ASA I-III,moderate and severe OSAHS patients between 18-65 years old undergoing elective UPPP.
Exclusion criteria
Exclusion criteria: Exclusion criteria were patients with relative or absolute contraindication to the use of lidocaine (allergy to local anesthetics,changes in atrioventricular conduction,severe liver and kidney dysfunction,uncontrolled epilepsy,porphyria,and malignant hyperthermia),those receiving antidepressants and/or anticonvulsants,with cardiac arrhythmia and any type of rheumatic disease,patients who do not understand QoR-40 and/or have used opioids in the past 24 h.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS);Sufentanil consumption;Flurbiprofen requirements in PACU;NO;ET;Extubation time; | — |
Countries
China
Contacts
Public ContactChenglan Xie
The Affiliated Huaian Hospital of Xuzhou Medical university/Huai 'an Second Hospital
Outcome results
None listed