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Feasibility of Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy in Breast Cancer

Feasibility of Sentinel Lymph Node Biopsy after Neoadjuvant Chemotherapy in Breast Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800014968
Enrollment
Unknown
Registered
2018-02-25
Start date
2016-01-01
Completion date
Unknown
Last updated
2018-03-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Case series:sentinel lymph node biopsy

Sponsors

Cancer Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
27 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Female patient (2) The seventh edition of the AJCC Cancer Staging Manual belongs to patients with stage II-III invasive breast cancer; (2) No evidence of distant metastasis at baseline; (3) The core niddle biopsy (CNB) was used to determine the pathological type and the fine niddle aspiration (FNA) was used to confirm the axillary lymph node metastasis. (4) Taxanes, anthracyclines, platinum and other drugs neoadjuvant chemotherapy over 6 cycles (5) After neoadjuvant chemotherapy, both breast and axillary ultrasonography and MRI were performed to evaluate the axillary lymph node metastasis and surgical treatment in our hospital (according to the tumor size, location, patients' wishes and other factors, choose breast-conserving or modified radical cure); (6) The above first diagnosis, neoadjuvant chemotherapy, imaging acquisition, biopsy, imaging examination, surgical treatment and pathological examination were completed in our hospital.

Exclusion criteria

Exclusion criteria: (1) drugs such as taxanes, anthracyclines, platinum and other drugs less than 6 cycles of neoadjuvant chemotherapy, or midway replacement chemotherapy; (2) imaging or medical history information is not included in the group; (3) distant metastasis signs have appeared; (4) patients due to severe heart and lung dysfunction, can not tolerate surgery; (5) The patient withdraw from the study halfway through other reasons unrelated to the project for any physical or social reasons.

Design outcomes

Primary

MeasureTime frame
identification rate;

Countries

China

Contacts

Public ContactXin Wang

Cancer Hospital, Chinese Academy of Medical Sciences

pumcwangstar@live.cn+86 15001202723

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026