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The role of TREM in cognitive dysfunction after knee arthroplasty in elderly patients

The role of TREM in cognitive dysfunction after knee arthroplasty in elderly patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014928
Enrollment
Unknown
Registered
2018-02-23
Start date
2018-02-21
Completion date
Unknown
Last updated
2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

POCD

Interventions

Group 2:Dexmedetomidine
Group 1:no intervention

Sponsors

Qingdao Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Aged 65-85 years male and female; 2. ASA I-III; 3. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Preoperative MMSE < 23; 2. Heart rate < 50 beats/min; 3. Heart block disease; 4. Patients with neurological, mental illness, tumor; 5. Hearing, reading, reading and writing in Chinese; 6. Secondary operation; 7. Previous history of oncology.

Design outcomes

Primary

MeasureTime frame
TREM;—

Secondary

MeasureTime frame
IL-6;TNF-a;Aß;—

Countries

China

Contacts

Public ContactYanLin BI

Department of Anesthesiology, Eastern Compus of Qingdao City Hospital, Shandong

yanlinbi68@sina.cn+86 18661675610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026