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The clinical application of THRIVE in preoxygenation and prolonging the duration of apnea without desaturation during peri-intubation period

The clinical application of THRIVE in preoxygenation and prolonging the duration of apnea without desaturation during peri-intubation period

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014921
Enrollment
Unknown
Registered
2018-02-22
Start date
2018-03-01
Completion date
Unknown
Last updated
2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway Management

Interventions

Facemask Group:Preoxygenation via facemask before anesthesia induction, controlled ventilation via facemask during anesthesia induction, no special ventilatory intervention will be performed during tr
Facemask plus THRIVE Group:Preoxygenation via facemask before anesthesia induction, controlled ventilation via facemask during anesthesia induction, and THRIVE will be applied during tracheal intubati
THRIVE:THRIVE will be applied during preoxygenation, anesthesia induction and tracheal intubation
THRIVE plus NPA Group:with NPA placement, THRIVE will be applied during preoxygenation, anesthesia induction and tracheal intubation

Sponsors

Sun Yat-sen Memorial hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 75 Years

Inclusion criteria

Inclusion criteria: ASA I-III, Mallampatti Score I-III patients undergoing selective laparascopic procedure.

Exclusion criteria

Exclusion criteria: age75 years, body weight30, comorbidities as following: mild and severe anemia; CNS abnormality; grade 2 or 3 hypertension, NYHA Class II or over, other cardiovascular disease; anticipated difficult airway, post tracheotomy, airway obstruction (including nasal pharyngeal abnormality, OSAS); pulmonary disease (including pneumonia, COPD, asthma); digestive disease (including full stomach, ileus, gastric perforation).

Design outcomes

Primary

MeasureTime frame
Changes of PaO2 during apneic tracheal intubation;

Secondary

MeasureTime frame
PaO2;PaCO2;HR, MAP;

Countries

China

Contacts

Public ContactJun Peng

Sun Yat-sen Memorial hospital, Sun Yat-sen University

pengjun2@mail.sysu.edu.cn+86 13763381017

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026