Schizophrenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. According to DSM-IV diagnostic criteria for schizophrenia; 2. Aged >= 18 years; 3. Disease course more than 5 years; 4. Experiencing residual symptoms of hallucination and/or delusions (subscale P3 score on the PANSS >= 5, and/or out of the subscale items P1, P5, P6, G1, G3 and G9, scores for at least two of them >= 5); 5. Stable condition; 6. MMSE >= 24; 7. The patients were approved by the hospital ethics committee and the patients signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Major Axis I disorder; 2. Obviously impaired cognitive function; 3. Speech and communication disorder; 4. Severe physical diseases; 5. Substance abuse/dependence.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD5L level and its change;Reduction rate of PANSS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Short Form-36 Health Survey;Five Facet Mindfulness Questionnaire;EEG measurement;MRI measurement;PANSS score; | — |
Countries
China
Contacts
The first Minzheng Mental Health Center, Shanghai, China