idiopathic pulmonary hemosiderosis
Conditions
Interventions
Experimental group:Transplantation of hUC-MSCs
Control group:None
Sponsors
The Third Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
5 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. aged from 5-18 years old; 2. conforms to the IPH diagnostic criteria; 3. parents or guardians agree to treat and sign written informed consent.
Exclusion criteria
Exclusion criteria: 1. combined with severe underlying diseases, such as systemic systemic malignancies, heart failure, liver and renal failure, immunodeficiency, severe infectious diseases, and other indications for emergency operation after lung transplantation; 2. patients with other pulmonary diseases; 3. who had previously participated in the clinical trials of stem cell therapy; 4. researchers think it is not appropriate to take part in other situations in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Episodes of annual pulmonary hemorrhage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions;serum iron metabolism;T lymphocyte subset;Pulmonary function tests;sputum induction test;plasma inflammatory factors test;Number of circulating fibroblasts; | — |
Countries
China
Contacts
Public ContactYa-Ting Li
The Third Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed