dyslipidemia
Conditions
Interventions
M:monacolin k-riched red yeast rice
G:Gamma-Aminobutryic Acid (GABA)-riched red yeast rice
Sponsors
development department, Gunze Limited, Japan
Eligibility
Sex/Gender
All
Age
29 Years to 64 Years
Inclusion criteria
Inclusion criteria: Before the exclusion were interviewed by internal medicinal physicians at Chang-Gung Memorial hospital in a preliminary screening, subjects met the criteria (LDL >100 mg/dl, TC > 200 mg/dl) will be included.
Exclusion criteria
Exclusion criteria: Some subjects were excluded from the study due to the following factors: 1) take hormone replacement therapy or immunosuppressive agents, 2) take the lipid-regulating drugs, 3) take the drugs known to affect lipid concentrations, 4) take the drugs known to be associated with rhabdomyolysis, cardiovascular disease, severe systemic and chronic disease, malignant neoplasm, 5) pregnancy, 6) receive insulin or oral hypoglycemic agents 7) have an endocrine disease related to lipid abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure, cholesterol, LDL, HDL, triglyceride, renal function, liver function and liver transaminase; | — |
Secondary
| Measure | Time frame |
|---|---|
| monacolin K, C-reactive protein, incidences of acute cardiovascular events, Interleukin-6, C-reactive protein (CRP) and inflammation related immune cells (CD4+ T cells, NK cells); | — |
Countries
China
Contacts
Public ContactSien-Hung Yang
Chang Gung Memorial Hospital
Outcome results
None listed