Lung cancer
Conditions
Interventions
1:Tranexamic acid 0.125mg preoperative inhalation for half an hour
2:Tranexamic acid 0.25mg preoperative inhalation for half an hour
3:2% lidocaine 5ml preoperative inhalation for half an hour (control group)
Sponsors
Jinhua Municipal Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. adult patients aged 18-80 with endobronchial local exophytic lesions who underwent EBB, and patients diagnosed with primary lung cancer based on histological confirmation; 2. The subject / legal authorized representative understands the purpose and procedure of the trial and voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Immunosuppression; 2. active bleeding, known bleeding tendencies, or a suspected bleeding disorder; 3. Continuous anti-coagulant or anti-platelet therapy; 4. Heart function failure, liver or kidney disease;echanical ventilation; 5. Lung transplant; 6. Pulmonary arterial hypertension 7. Thrombocytopaenia (platelets 1.3; 8. Hemophilia; 9. Thrombophilia or thrombosis in patients already; 10. Allergic to Tranexamic acid, and intolerate anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemorrhage; | — |
Countries
China
Contacts
Public ContactSaibin Wang
Jinhua Municipal Central Hospital
Outcome results
None listed