postoperative complications
Conditions
Interventions
high BIS group:Bis maintained at 50+/-5 during surgery
low BIS group:Bis maintained at 35+/-5 during surgery
Sponsors
The 3rd Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
70 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Age =70 years old; 2) plan to take elective non-cardiac surgery under general anesthesia, expected surgery time =2h; 3) agree to participate in this study and sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1) refuse to participate in this study; 2) history of schizophrenia, epilepsy, Parkinson's disease or myasthenia gravis; 3) incomplete preoperative assessment due to severe dementia, speech impairment, coma, end-stage disease; 4) severe renal impairment (renal replacement therapy required); severe liver impairment (Child-Pugh grade C); patients expected to survive =24 hours; 5) brain surgery; 6) other situations supported by the attending physician or researcher (reasons should be documented).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative complications within 30 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative mortality;NRS pain score during the first 3 days after surgery;Cognitive function at the 7th day after surgery;Cognitive function at the 30 days after surgery; | — |
Countries
China
Contacts
Public ContactWen OUYANG
The 3rd Xiangya Hospital of Central South University
Outcome results
None listed