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Additional dose of cocktail analgesic pain rebound after total knee arthroplasty: a randomized controlled trial

Additional dose of cocktail analgesic pain rebound after total knee arthroplasty: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800014838
Enrollment
Unknown
Registered
2018-02-08
Start date
2018-03-01
Completion date
Unknown
Last updated
2018-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

1:additional dose of cocktail anaesthetic intraarticular infusion
2:additional dose of saline intraarticular infusion

Sponsors

Nanxiong Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for knee osteoarthritis; 2. American Society of Anesthesiologists (ASA) physical status I-II; 3. Scheduled for unilateral total knee arthroplasty; 4. Patients aged 50~80 years old.

Exclusion criteria

Exclusion criteria: 1. Unwillingness of the patient; 2. Presence of neuropathic pain or sensory disorders in the leg to be operated on; 3. Intolerance to the study drugs; 4. Previous major knee surgery, re-operation or trauma to the knee within the study period.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale;active range of motion;post-op infection markers;rescue analgesia and adverse event;—

Countries

China

Contacts

Public ContactBingshan Zhang

Nanxiong Hospital of Chinese Medicine

15509543@qq.com+86 13600298950

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026