disorder of consciousness
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
16 Years to 80 Years
Inclusion criteria
Inclusion criteria: Coma: (1) Male and female aged 16-80 years; (2) severe brain injury that leads to coma (including trauma, cerebrovascular disease, ischemic hypoxic encephalopathy or other severe brain injury); (3) coma lasts more than a week; (4) imaging (MRI) head has no obvious shift, missing, large necrosis of brain structure change and obvious brain stem (not including pyramidal tract) or thalamic lesions, each lobe lesions range can not exceed 30% of the scope of one side of the brain; (5) stable condition and stable symptoms; (6) the family members of the patient volunteered to participate in the study and signed informed consent. Plant status and Minimum state of consciousness: (1) Male and female aged 18-65 years; (2) in line with the establishment of the multi-society Task Force in 1994 and the current internationally recognized standards for plant status diagnosis;conforming to the current internationally recognized minimum state diagnostic criteria for international studies, such as Giacino in 2002; (3) the course of illness is more than one month; (4) imaging (MRI) head has no obvious shift, missing, large necrosis of brain structure change and obvious brain stem (not including pyramidal tract) or thalamic lesions, each lobe lesions range can not exceed 30% of the scope of one side of the brain; (5) stable condition and stable symptoms; (6) the family members of the patient volunteered to participate in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) the use of sedative sleeping pills, anesthetics, psychotropic drugs, muscle relaxants or Na +, ca+ + channel blockers (such as carbamazy equality) during the evaluation period; (2) ventilator dependence; (3) the course of illness is over 1 year; (4) there electromagnetism examination and treatment of the taboo, including metal material is contained inside the body, such as pacemakers, dentures, steel nails, etc.), open craniocerebral injury or skull defect prevents the line electromagnetic stimulation; (5) there was a history of epileptic seizures, and patients with epileptic seizures or eeg were clinically indicated; (6) the combination of other serious diseases (such as heart, liver and kidney failure); (7) progressive neurological diseases such as central nervous system tumor or transsexual disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glasgow Outcome Scale, GOS;Glasgow Coma Scale, GCS; | — |
Secondary
| Measure | Time frame |
|---|---|
| event-related potential, ERP; | — |
Countries
China
Contacts
Public ContactWeiming SUN
The First Affiliated Hospital of Nanchang University
Outcome results
None listed