Spine Surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Sixty patients aged between 19 and 79 years, American Society of Anesthesiologists physical status I–II, undergoing elective lumbar spine surgery (surgical time > 180 min), including posterolateral fusion and pedicle screw fixation, were recruited. Study recruitment took place between July 12, 2008 and December 2, 2009.
Exclusion criteria
Exclusion criteria: Patients were excluded when they had cardiopulmonary, endocrinologic, or immunologic diseases, malignancies, spine deformity, chronic pain management, or there was difficulty in the assessment of postoperative pain (e.g., postoperative mechanical ventilation), early termination of patient-controlled analgesia (PCA) due to deterioration of patient condition, or when the patients required a second operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cytokines; | — |